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. Author manuscript; available in PMC: 2013 Apr 23.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2013 Feb 18;6(2):392–401. doi: 10.1161/CIRCEP.111.000206

Figure 6. Knockdown of MOG1 expression causes retention of Nav1.5 in the ER and the redistribution of Nav1.5 from caveolin-3 enriched fractions and other fractions.

Figure 6

A. Relative amounts of Nav1.5 in the RER-enriched fractions of HEK/Nav1.5 cells analyzed by WB analysis (10% gel). Calnexin (an ER marker), loading control. B. HEK/Nav1.5 cells were transiently transfected with an expression plasmid for caveolin-3. Cell lysates were fractionated, one ml of fractions (a total of 12 fractions) were collected from the top of the gradient and analyzed by WB (10% gel) with antibodies against Nav1.5, MOG1 or caveolin-3 (Cav-3). The experiment was repeated three times.