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. Author manuscript; available in PMC: 2013 Apr 23.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2000 Feb;278(2):H595–H603. doi: 10.1152/ajpheart.2000.278.2.H595

Table 3.

Regional left ventricular function

Baseline
Preischemic Treatment
Ischemia
Reperfusion
Control GIK Control GIK Control GIK Control GIK
Anterior LV
Preload
 Steady-state end-diastolic crystal area 1 1 1.00±0.01 1.00±0.01 1.17±0.03* 1.13±0.02* 1.09±0.05 1.10±0.04*
Systolic function
 Steady-state external work 1 1 0.97±0.03 0.95±0.03 0.21±0.05* 0.32±0.04* 0.18±0.06* 0.38±0.05*
 Fractional systolic wall area reduction 0.28±0.02 0.29±0.02 0.28±0.02 0.29±0.02 −0.02±0.02* 0.08±0.01* 0.01±0.02* 0.11±0.01*
Diastolic function
 dA/dtmax 1 1 0.99±0.04 1.01±0.06 0.62±0.04* 0.92±0.11 0.52±0.07* 0.77±0.05*
Posterior LV
Preload
 Steady-state end-diastolic crystal area 1 1 0.97±0.02 1.00±0.01 1.04±0.02 1.09±0.03* 1.02±0.02 1.07±0.03*
Systolic function
 Steady-state external work 1 1 0.99±0.04 0.99±0.02 0.93±0.04 0.95±0.05 0.83±0.02* 0.87±0.07
 Fractional systolic wall area reduction 0.27±0.03 0.29±0.02 0.26±0.03 0.28±0.02 0.32±0.03* 0.34±0.01* 0.29±0.06 0.31±0.01
Diastolic function
 dA/dtmax 1 1 0.94±0.04 0.98±0.03 0.90±0.09 0.90±0.08 0.90±0.10 0.90±0.09

Values are means ± SE; n = 8 in each group. dA/dtmax, maximum rate of diastolic wall area expansion with respect to time. Except for fractional systolic wall area reduction, all values are expressed as fraction of baseline.

*

P < 0.05 vs. baseline within same group.

P < 0.05 and

P < 0.01 vs. control group under same condition.