Table 4.
Baseline |
Preischemic Treatment |
Ischemia |
Reperfusion |
|||||
---|---|---|---|---|---|---|---|---|
Control | GIK | Control | GIK | Control | GIK | Control | GIK | |
Heart rate, min−1 | 111±2 | 112±2 | 110±1 | 112±2 | 110±1 | 113±2 | 111±1 | 113±2 |
Mean aortic pressure, mmHg | 98±3 | 97±1 | 94±5 | 100±4 | 87±5 | 86±7 | 85±5 | 85±8 |
LV systolic pressure, mmHg | 104±4 | 112±5 | 102±5 | 112±5 | 94±5 | 96±5 | 90±4 | 93±6 |
LV end-diastolic pressure, mmHg | 8±1 | 8±1 | 8±1 | 8±1 | 14±2* | 11±1* | 14±2* | 11±2* |
LA mean pressure, mmHg | 4±1 | 5±1 | 4±1 | 5±1 | 7±2 | 8±1 | 9±2 | 9±1 |
LV +dP/dtmax Fraction of baseline, mmHg/s | 1 (1,792±124) | 1 (1,534±112) | 1.02±0.01 | 0.99±0.01 | 0.75±0.03* | 0.92±0.02‡ | 0.62±0.02* | 0.82±0.04*† |
LV −dP/dtmax Fraction of baseline, mmHg/s | 1 (−2,534±335) | 1 (−2,118±205) | 0.98±0.02 | 1.03±0.02 | 0.68±0.04* | 0.81±0.04*† | 0.61±0.03* | 0.82±0.07*† |
Values are means = SE; n = 8 in each group. LA, left atrial; dP/dtmax, maximum change in pressure with respect to time.
P < 0.05 vs. baseline within same group.
P < 0.05 and
P < 0.01 vs. control group under same condition.