Fig. 3.
Mean (±SEM) crossover latencies (s) on testing day for gonadectomized rats administered vehicle control (vehicle; open bar), or 3α-diol-replaced gonadectomized rats administered saline to the hippocampus (3α-diol, closed bar), scrambled ODN (ER scrambled; horizontally striped bar), ER AS-ODN (ERα and ERβ; vertically striped bar), ERα AS-ODN (ERα; stippled bar), or ERβ AS-ODN (ERβ; diagonally striped bar). * denotes a significant difference (p < 0.05) from control. (n = 6/group). Inset depicts representative images of ERα, ERβ, and actin protein levels in the hippocampus of rats administered ERα and ERβ AS-ODN, and in the pituitary of vehicle control rats.