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. Author manuscript; available in PMC: 2013 Apr 23.
Published in final edited form as: Breast Cancer Res Treat. 2009 Jul 11;121(1):65–78. doi: 10.1007/s10549-009-0457-3

Figure 7.

Figure 7

Taxol promotes tumor cell-ECM binding. Equivalent concentrations of MDA-436 cells were plated over gelatin-coated coverslips in serum-free media supplemented with 500nMjas (C and D), 1.17μMTaxol (E and F), jas + Taxol (G and H) or 125μM colchicine (I and J). After 45 minutes, unattached cells were removed by gentle aspiration and washing, and attached cells were fixed and labeled with a nuclear dye (A, C, E, G, I) and a fluorescent phalloidin conjugate (B, D, F, H, J). Images were captured at 10X magnification, revealing differences in total numbers of attached cells.