Fig. 7.
Effect of chronic troglitazone treatment on myocardial free fatty acid (FFA) uptake. Myocardial FFA uptake is plotted as a function of arterial FFA concentration ([FFA]) under nonischemic, ischemic, and reperfusion conditions for 14 untreated pigs and 12 troglitazone-pretreated pigs. In 6 pigs from each group, arterial FFA concentrations were increased by infusion of triglyceride emulsion (10% Liposyn) and heparin. Lines indicate linear regression of data. Chronic troglitazone treatment had no significant effect on myocardial FFA uptake under any condition.