Agar diffusion competition assay for conjugates 3b and 3c and siderophores 3a, 3a-Fe, DFO-B, and FO-B tested against S. aureus SG511. Siderophores 3a, 3a-Fe, DFO-B, and FO-B clearly antagonize the anti-S. aureus activity of the fluoroquinolone conjugate 3c (c,d), but not the β-lactam conjugate 3b (a, b). Images are not to actual scale.