Table 2.
Test Organism |
|||
---|---|---|---|
Staphylococcus aureus SG511 |
|||
Entry | Compound | MHII + Feb | MHII − Fec |
1 | 1b | 16 | 16 |
2 | 2b | 128 | 64 |
3 | 3b | 128 | 64 |
4 | 1c | 64 | 32 |
5 | 2c | 64 | 64 |
6 | 3c | 4 | 1 |
8 | Lorabid® | 1 | 1 |
9 | ciprofloxacin | 0.5 | 0.5 |
MIC values were determined using the broth microdilution method using visual end point analysis according to the CLSI guidelines.(40)
Each compound was tested in triplicate.
MHII + Fe: Mueller-Hinton Broth No. 2 + 100 µM FeCl3.
MHII − Fe: Mueller-Hinton Broth No. 2 + 100 µM 2,2’-bipyridine.