Table 3.

MIC values (µM) of compounds 1b–3b and 1c–3c against S. aureus SG511 in the presence of competing siderophores.^a,^b,^c

		Test Organism
		Staphylococcus aureus SG511
Entry	Compoundd	MHII − Fee
1	1b + 1a	16
2	1b + DFO-B	16
3	2b + 2a	32
4	2b + DFO-B	16
5	3b + 3a	32
6	3b + 3a-Fe	64
7	3b + DFO-B	32
8	3b + FO-B	64
9	1c + 1a	32
10	1c + DFO-B	16
11	2c + 2a	64
12	2c + DFO-B	64
13	3c + 3a	1
14	3c + 3a-Fe	1
15	3c + DFO-B	128
16	3c + FO-B	>128

^aMIC values were determined using the broth microdilution method using visual end point analysis according to the CLSI guidelines.(40)

^bEach compound was tested in triplicate.

^cData presented here should be compared to MIC values in Table 1 for compounds 1b–3b and 1c– 3c.

^dCompounds were tested as 1:1 molar mixtures.

^eMHII – Fe: Mueller-Hinton Broth No. 2 + 100 µM 2,2’-bipyridine