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Frequent chromosomal region abnormalities in neuroblastoma
| Chromosomal region | Status | Frequency | Relation with MYCN amplification | Involved genes | Clinical group |
|---|---|---|---|---|---|
| 1p36 | Loss | 25–35% | Correlation | CHD5, miR-34a, KIF1Bβ | Unfavorable |
| 11q23 | Loss | 35–45% | Inversed correlation | TSLC1/IGSF4 | Unfavorable |
| 14q23 | Loss | 16–27% | Inversed correlation | All groups | |
| 17q22 | Gain | ~50% | Correlation | Survivin, NM23A | Unfavorable |
