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. Author manuscript; available in PMC: 2013 Apr 23.
Published in final edited form as: Eur J Neurosci. 2007 Sep 6;26(6):1479–1488. doi: 10.1111/j.1460-9568.2007.05775.x

Fig. 3.

Fig. 3

Paired-pulse depression was presynaptic. (A) Paired-pulse inhibition was not observed when dopamine (1 m) was applied exogenously through iontophoresis (dark arrows). Furthermore, a large iontophoretic pulse did not depress the dopamine IPSC. (B, bottom trace) Two IPSCs (stim-1 and stim-2) separated by 4 s exhibited paired-pulse depression. (B, top trace) In the same cell a large iontophoretic pulse (ionto) did not depress the dopamine IPSC evoked 4 s later (ionto/stim). (C) IPSC tracings from this experiment are overlaid, showing that paired stimuli produced depression while iontophoresis of dopamine did not.