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. Author manuscript; available in PMC: 2013 Apr 23.
Published in final edited form as: Eur J Neurosci. 2007 Sep 6;26(6):1479–1488. doi: 10.1111/j.1460-9568.2007.05775.x

Fig. 4.

Fig. 4

Fast-scan cyclic voltammetry determination of the regulation of dopamine release from the VTA by D2 autoreceptors. (A) Summarized voltammetric current vs. time responses were generated by three pulses at 5 Hz (n = 7) under control conditions and in the presence of sulpiride (200 nm). (Inset) Cyclic voltammagrams recorded at the peak of the stimulated dopamine response and after the exogenous application of dopamine with iontophoresis (100 nA, 50 ms). Peak oxidation and reduction peaks were +637 and –352 mV for the electrically evoked signal and +609 and –352 mV for the exogenous dopamine signal. Voltammagrams were generated by a voltage waveform from –0.4 to +1.0 V at 300 V/s. (B) Summarized voltammetric current vs. time responses were generated by three pulses at 5 Hz (n = 9) under control conditions, in the presence of cocaine (1 μm) and cocaine (1 μm) + sulpiride (200 nm).