Table 1.
Characteristic | Cases (n = 552 951) | Controls (n = 100 000) | p-value | ||
---|---|---|---|---|---|
N | Percent % | N | Percent % | ||
Sex | |||||
Male | 280 034 | 50.6 | 50 644 | 50.6 | 1.00 |
Female | 272 917 | 49.4 | 49 356 | 49.4 | |
Age at diagnosis or selection (years) | |||||
70–74 | 159 254 | 28.8 | 28 800 | 28.8 | 1.00 |
75–79 | 167 536 | 30.3 | 30 299 | 30.3 | |
80–84 | 126 165 | 22.8 | 22 817 | 22.8 | |
85–99 | 99 996 | 18.1 | 18 084 | 18.1 | |
Median (Range) | 78 (70–99) | 78 (70–99) | |||
Selection year | |||||
1997–1999 | 110 534 | 20.0 | 19 989 | 20.0 | 1.00 |
2000–2001 | 153 125 | 27.7 | 27 692 | 27.7 | |
2002–2003 | 147 348 | 26.7 | 26 648 | 26.7 | |
2004–2005 | 141 944 | 25.7 | 25 671 | 25.7 | |
Race | |||||
White | 482 412 | 87.2 | 85 394 | 85.4 | <.0001 |
Black | 39 249 | 7.1 | 6 462 | 6.5 | |
Asian | 13 105 | 2.4 | 3 378 | 3.4 | |
Other or unknown | 18 185 | 3.3 | 4 766 | 4.8 | |
Any Condition 0–12 months | |||||
No | 42 331 | 7.7 | 8 488 | 8.5 | <.0001 |
Yes | 510 620 | 92.3 | 91 512 | 91.5 | |
Any Condition 13–30 months | |||||
No | 49 773 | 9.0 | 9 496 | 9.5 | <.0001 |
Yes | 503 178 | 91.0 | 90 504 | 90.5 | |
Any Condition 31–48 months | |||||
No | 60 592 | 11.0 | 11 153 | 11.2 | 0.070 |
Yes | 492 359 | 89.0 | 88 847 | 88.9 | |
Total number of conditions 0–12 months | |||||
0 | 42 331 | 7.7 | 8 488 | 8.5 | <.0001 |
1 | 40 163 | 7.3 | 7 537 | 7.5 | |
2 | 50 909 | 9.2 | 9 711 | 9.7 | |
3+ | 419 548 | 75.9 | 74 264 | 74.3 | |
Median (Range) | 5 (0–44) | 5 (0–36) | |||
Total number of conditions 13–30 months | |||||
0 | 49 773 | 9.0 | 9 496 | 9.5 | <.0001 |
1 | 46 054 | 8.3 | 8 570 | 8.6 | |
2 | 56 767 | 10.3 | 10 657 | 10.7 | |
3+ | 400 357 | 72.4 | 71 277 | 71.3 | |
Median (Range) | 4 (0–40) | 4 (0–34) | |||
Total number of conditions 31–48 months | |||||
0 | 60 592 | 11.0 | 11 153 | 11.2 | 0.006 |
1 | 54 677 | 9.9 | 9 923 | 9.9 | |
2 | 64 258 | 11.6 | 11 913 | 11.9 | |
3+ | 373 424 | 67.5 | 67 011 | 67.0 | |
Median (Range) | 4 (0–38) | 4 (0–31) |