Figure 3. Altered cytokine expression in E. muris infection in the absence of MyD88-signaling.
(A) Serum IFNγ and IL-12p70 were evaluated in C57BL/6, MyD88-deficient, and mixed chimeric mice on day 11 post-E.muris infection. (B) Bone marrow homogenate was analyzed for IFNγ and IL-12p70 on day 11 post-infection. Statistically significant differences are indicated as follows: # represents differences between strains of mice, and * represent differences between mock and infected groups; n.s. indicates no significance. Data were from two separate experiments, and at least three mice were assayed within each group.