Figure 4. Blockade of fatty-acid synthesis enhances DC capacity for antigen capture in vitro and in vivo.
(a–c) BMDC and T-BMDC were tested at various time points for uptake of fluorescent (a) Albumin, (b) Dextran, and (c) Mannosylated Albumin (*p<0.05; **p<0.01; ***p<0.001). (d) Splenic CD11c+ cells from control or C75 treated mice were tested for uptake of FITC-Albumin at 30 minutes after in vivo administration. Data are representative of experiments performed 3 times.