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Small intestinal and colonic permeability by the cumulative mannitol (A) and lactulose (B) excretion at 0–2h and 8–24h, respectively. There was increased small intestinal permeability with GCD, as shown by both cumulative mannitol excretion and lactulose to mannitol ratio (ITT analysis, # p=0.028 and p=0.0012). The effect on lactulose excretion was borderline significant (* p=0.097).
