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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Pediatr Obes. 2013 Jan 16;8(6):10.1111/j.2047-6310.2012.00127.x. doi: 10.1111/j.2047-6310.2012.00127.x

Table 2. Associations of maternal and early life anthropometric parameters with child adiponectin and leptin levels at age 9.

9 Year Child
Adiponectin (μg/ml) Leptin (logged)

Characteristic N Mean1±SD%CI) Beta2 (95% CI) P Beta (95% CI) P

Birth Weight (kg)
Crude3 146 3.5 ±0.5 (3.4, 3.6) −4.7 (−12.0, 2.6) 0.2 0.12 (−0.08, 0.31) 0.26
Adjusted3,4 146 −1.6 (−8.6, 5.3) 0.64 −0.06 (−0.19, 0.08) 0.4
Birth Length (cm)
Crude3 146 50.5 ±2.6 (50.0, 50.9) −0.2 (−1.5,1.2) 0.83 0.02 (−0.01, 0.06) 0.23
Adjusted3,4 146 −0.1 (−1.4,1.2) 0.88 0.02 (−0.01, 0.05) 0.12
Weight Gain in First 6 Months of Life (lOOg/month)
Crude 133 7.4 ±1.6 (7.1, 7.7) −2.8 (−4.8, −0.8) 0.007 0.04 (−0.01, 0.1) 0.15
Adjusted4 133 −2.0 (−1.79, −0.5) 0.04 0.01 (−0.05, 0.03) 0.61
Length Gain in First 6 Months of Life (cm/month)
Crude 133 2.6 ±0.5 (2.5, 2.7) −9.7 (−16.7,−2.8) 0.007 −0.001 (−0.19, 0.19) 0.99
Adjusted4 133 −8.2 (−15.0,−1.5) 0.02 −0.1 (−0.23, 0.03) 0.14
Child 9Y Adiponectin (μg/ml)
Crude 146 44.2 ±18.8 (41.1,47.2) ----- −0.007 (−0.01,−0.002) 0.003
Adjusted4 146 ----- 0.001 (−0.002, 0.004) 0.56
Child 9Y Leptin
Crude 146 7.6 ±3.2 (6.3, 9.2) −8.9 (−14.7,−3.0) 0.003 -----
Adjusted4 146 2.5 (−5.9,10.8) 0.56 -----
Pre-Pregnancy BMI
Crude 146 27.4 ±5.4 (26.5, 28.2) −0.8 (−1.4, −0.2) 0.006 0.03 (0.01, 0.04) <0.001
Adjusted4 146 −0.3 (−0.9, .3) 0.28 0.001 (−0.01, 0.01) 0.84
Weight Gain During Pregnancy (kg)
Crude 146 13.2 ±5.1 (12.4,14.0) −0.1 (−0.8, 0.5) 0.65 0.01 (−0.01, 0.02) 0.43
Adjusted4 146 0.03 (−0.5, 0.6) 0.91 −0.003 (−0.01, 0.01) 0.61
Maternal Adiponectin At 9 Year Visit (μg/ml)
Crude 146 29.2 ±13.7 (26.9, 31.4) 0.4(0.2, 0.6) <0.001 −0.0002 (−0.01, 0.01) 0.95
Adjusted4 146 0.3(0.1, 0.6) 0.001 0.003 (−0.002, 0.01) 0.23
Maternal Leptin At 9 Year Visit
Crude 146 22.3 ±2.4 (19.3, 25.7) −9.3 (−17.4,−1.2) 0.02 0.42(0.21, 0.63) <0.001
Adjusted4 146 −5.9 (−13.7,1.8) 0.13 0.23 (0.08, 0.38) 0.002
1

Geometric mean for leptin.

2

Linear regression estimate.

3

Model adjusted for gestational age.

4

Model adjusted for 9-year child BMI.