Table 2. Associations of maternal and early life anthropometric parameters with child adiponectin and leptin levels at age 9.
9 Year Child | ||||||
---|---|---|---|---|---|---|
Adiponectin (μg/ml) | Leptin (logged) | |||||
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Characteristic | N | Mean1±SD%CI) | Beta2 (95% CI) | P | Beta (95% CI) | P |
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Birth Weight (kg) | ||||||
Crude3 | 146 | 3.5 ±0.5 (3.4, 3.6) | −4.7 (−12.0, 2.6) | 0.2 | 0.12 (−0.08, 0.31) | 0.26 |
Adjusted3,4 | 146 | −1.6 (−8.6, 5.3) | 0.64 | −0.06 (−0.19, 0.08) | 0.4 | |
Birth Length (cm) | ||||||
Crude3 | 146 | 50.5 ±2.6 (50.0, 50.9) | −0.2 (−1.5,1.2) | 0.83 | 0.02 (−0.01, 0.06) | 0.23 |
Adjusted3,4 | 146 | −0.1 (−1.4,1.2) | 0.88 | 0.02 (−0.01, 0.05) | 0.12 | |
Weight Gain in First 6 Months of Life (lOOg/month) | ||||||
Crude | 133 | 7.4 ±1.6 (7.1, 7.7) | −2.8 (−4.8, −0.8) | 0.007 | 0.04 (−0.01, 0.1) | 0.15 |
Adjusted4 | 133 | −2.0 (−1.79, −0.5) | 0.04 | 0.01 (−0.05, 0.03) | 0.61 | |
Length Gain in First 6 Months of Life (cm/month) | ||||||
Crude | 133 | 2.6 ±0.5 (2.5, 2.7) | −9.7 (−16.7,−2.8) | 0.007 | −0.001 (−0.19, 0.19) | 0.99 |
Adjusted4 | 133 | −8.2 (−15.0,−1.5) | 0.02 | −0.1 (−0.23, 0.03) | 0.14 | |
Child 9Y Adiponectin (μg/ml) | ||||||
Crude | 146 | 44.2 ±18.8 (41.1,47.2) | ----- | −0.007 (−0.01,−0.002) | 0.003 | |
Adjusted4 | 146 | ----- | 0.001 (−0.002, 0.004) | 0.56 | ||
Child 9Y Leptin | ||||||
Crude | 146 | 7.6 ±3.2 (6.3, 9.2) | −8.9 (−14.7,−3.0) | 0.003 | ----- | |
Adjusted4 | 146 | 2.5 (−5.9,10.8) | 0.56 | ----- | ||
Pre-Pregnancy BMI | ||||||
Crude | 146 | 27.4 ±5.4 (26.5, 28.2) | −0.8 (−1.4, −0.2) | 0.006 | 0.03 (0.01, 0.04) | <0.001 |
Adjusted4 | 146 | −0.3 (−0.9, .3) | 0.28 | 0.001 (−0.01, 0.01) | 0.84 | |
Weight Gain During Pregnancy (kg) | ||||||
Crude | 146 | 13.2 ±5.1 (12.4,14.0) | −0.1 (−0.8, 0.5) | 0.65 | 0.01 (−0.01, 0.02) | 0.43 |
Adjusted4 | 146 | 0.03 (−0.5, 0.6) | 0.91 | −0.003 (−0.01, 0.01) | 0.61 | |
Maternal Adiponectin At 9 Year Visit (μg/ml) | ||||||
Crude | 146 | 29.2 ±13.7 (26.9, 31.4) | 0.4(0.2, 0.6) | <0.001 | −0.0002 (−0.01, 0.01) | 0.95 |
Adjusted4 | 146 | 0.3(0.1, 0.6) | 0.001 | 0.003 (−0.002, 0.01) | 0.23 | |
Maternal Leptin At 9 Year Visit | ||||||
Crude | 146 | 22.3 ±2.4 (19.3, 25.7) | −9.3 (−17.4,−1.2) | 0.02 | 0.42(0.21, 0.63) | <0.001 |
Adjusted4 | 146 | −5.9 (−13.7,1.8) | 0.13 | 0.23 (0.08, 0.38) | 0.002 |
Geometric mean for leptin.
Linear regression estimate.
Model adjusted for gestational age.
Model adjusted for 9-year child BMI.