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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Hear Res. 2013 Feb 9;299:63–78. doi: 10.1016/j.heares.2013.01.020

Figure 7. Dexamethasone induced nuclear translocation of GC-R in Hensen cells.

Figure 7

A significant (p≤0.05) increase in GC-R reactivity was observed in nuclei of Hensen cells treated with 10 μM (D, L, H, P) dexamethasone, when compared to untreated explants (A, E, I, M). No differences in nuclear expression of GC-R were observed in Hensen cell treated with 100 nM dexamethasone (C, G, K, O) respect to untreated ones. Although it was a perceptible increase in immunolabeling in Hensen cells treated with 10 pm (B, F, J, N), differences with the control condition were not statistically significant. Images of Hensen cell are shown at low magnification in A-H and higher magnification in I-P. Panels E-H and M-P are identical to panels A-D and I-L, respectively, except that the blue and red channels were turned off and GC R expression is shown in white to facilitate comparisons. Actin is shown in red and nuclei in blue in panels A-D and I-L whereas MC-R is shown in green in panels A-D and I-L or white in panels E-H and M-P.