Table II. Perforated Patch Data.
Data from perforated patch recording experiments performed as described in Fig. 1 are summarized for F11 clones wt-1 and i3-8 transfected with 5-HT1A receptor (wild-type or triple mutant). Other details are the same as in Table 1. For statistical significance see fig. 5.
| 30 mM Ca2+ [extracellular]
|
30 mM Ba2+ [extracellular]
|
|||||||
|---|---|---|---|---|---|---|---|---|
| N | % Inhib. before desensitization | % Inhib.after desensitization | % desensitization | N | % Inhib. before desensitization | %Inhib. after desensitization | % desensitization | |
| wt-1 | 7 | 64.1 ± 7.1 | 32.5 ± 8.6 | 52.7± 11.1 | 7 | 44.4 ± 4.9 | 29.3 ± 5.9 | 31.6 ± 11.3 |
| i3-8 | 9 | 70.8 ± 7.1 | 54.8 ± 7 | 21.5 ± 7.1 | 10 | 58.9 ± 5.8 | 59.9 ± 5.8 | −2.1 ± 4.7 |