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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Immunol. 2013 Mar 22;190(9):4562–4572. doi: 10.4049/jimmunol.1300091

Fig. 3. Long term, p75KO→F1 mice exhibit chronic rather than acute GVHD.

Fig. 3

Donor and host combinations are as described for Fig. 1. Mice were assessed at 20 weeks by flow cytometry for the following splenic lymphocyte subpopulations: A) host B cells; B) donor B cells; C) host CD11B+ APC; D) host cDC (CD11C+); E) host CD4 T cells; F) host CD8 T cells; G) donor CD4 T cells; and H) donor CD8 T cells. Mice received unfractionated donor splenocytes containing 7.1 ± 0.7 × 106 CD4 T cells and 4.6 ± 0.6 × 106 CD8 T cells. For normal F1, n=5; WT→F1 and p55→F1, n=4; p75KO→F1, n=6 and p55/p75 KO→F1, n=7.