Table 1. Mean biometric results from guinea pigs reared under the different lighting conditions over twelve weeks and the statistical results of the comparison between groups at each time-point.
| Groups | Time-point (week) eyes (n=12) |
|||||||
| 0 week | 2 weeks | 4 weeks | 6 weeks | 8 weeks | 10 weeks | 12 weeks | ||
| Refraction (D) | 5Hz | 4.02±0.19 | 2.33±0.87 | 1.35±0.68 | 0.81±1.12 | 0.67±1.24 | 0.55±1.17 | 0.53±1.15 |
| 1Hz | 4.17±0.25 | 1.98±0.58 | 0.58±0.58 | -0.11±0.73 | -0.46±0.73 | -0.77±0.91 | -0.63±1.23 | |
| 0.5Hz | 4.23±0.23 | 0.52±0.76 | -0.92±1.07 | -1.69±1.01 | -2.02±1.21 | -2.34±1.34 | -2.62±1.23 | |
| 0.25Hz | 4.13±0.25 | 1.42±0.68 | 0.46±1.01 | 0.17±1.03 | 0.08±1.49 | 0.15±1.51 | 0.17±1.66 | |
| 0.1Hz | 4.23±0.19 | 2.08±0.53 | 1.29±1.02 | 1.17±0.89 | 0.92±0.97 | 0.81±0.91 | 0.81±1.14 | |
| Control | 4.23±0.13 | 3.81±0.40 | 3.25±0.56 | 3.08±0.51 | 2.92±0.56 | 2.83±0.61 | 2.70±0.67 | |
| F | 1.86 | 33.2 | 31.4 | 36.3 | 27.4 | 29.2 | 26.2 | |
| P | 0.114 | <0.01 | <0.01 | <0.01 | <0.01 | <0.01 | <0.01 | |
| Axial length(mm) | 5Hz | 6.95±0.22 | 7.39±0.15 | 7.69±0.25 | 7.82±0.16 | 7.96±0.98 | 8.05±0.09 | 8.17±0.13 |
| 1Hz | 6.91±0.09 | 7.72±0.11 | 7.96±0.12 | 8.00±0.12 | 8.05±0.15 | 8.19±0.04 | 8.29±0.08 | |
| 0.5Hz | 6.86±0.14 | 7.79±0.16 | 8.28±0.42 | 8.35±0.27 | 8.41±0.19 | 8.46±0.16 | 8.47±0.16 | |
| 0.25Hz | 6.89±0.09 | 7.34±0.14 | 7.68±0.07 | 7.81±0.03 | 7.95±0.11 | 8.04±0.19 | 8.25±0.29 | |
| 0.1Hz | 6.89±0.10 | 7.46±0.10 | 7.77±0.07 | 7.82±0.06 | 7.94±0.64 | 7.98±0.04 | 8.05±0.29 | |
| Control | 6.89±0.09 | 7.33±0.07 | 7.48±0.08 | 7.57±0.09 | 7.62±0.06 | 7.76±0.25 | 7.79±0.21 | |
| F | 0.56 | 30.3 | 20.5 | 37.9 | 51.0 | 27.6 | 11.4 | |
| P | 0.73 | <0.01 | <0.01 | <0.01 | <0.01 | <0.01 | <0.01 | |
| Radius of corneal curvature (mm) | 5Hz | 3.15±0.06 | 3.39±0.13 | 3.49±0.27 | 3.51±0.16 | 3.53±0.09 | 3.58±0.17 | 3.64±0.32 |
| 1Hz | 3.15±0.06 | 3.36±0.12 | 3.46±0.26 | 3.49±0.15 | 3.52±0.09 | 3.58±0.13 | 3.64±0.24 | |
| 0.5Hz | 3.17±0.13 | 3.32±0.15 | 3.43±0.11 | 3.48±0.08 | 3.52±0.08 | 3.56±0.05 | 3.59±0.03 | |
| 0.25Hz | 3.26±0.29 | 3.31±0.22 | 3.43±0.14 | 3.46±0.12 | 3.48±0.13 | 3.55±0.08 | 3.62±0.09 | |
| 0.1Hz | 3.29±0.29 | 3.33±0.20 | 3.44±0.22 | 3.47±0.11 | 3.49±0.11 | 3.56±0.09 | 3.63±0.11 | |
| Control | 3.14±0.11 | 3.33±0.17 | 3.46±0.16 | 3.47±0.08 | 3.49±0.04 | 3.55±0.04 | 3.61±0.09 | |
| F | 1.43 | 0.34 | 0.15 | 0.29 | 0.42 | 0.15 | 0.07 | |
| P | 0.23 | 0.89 | 0.98 | 0.92 | 0.83 | 0.98 | 0.99 | |
“P” represents the significance of the inter-group differences using ANOVA.
x±s