Table 2:
Summary of some studies carried out on Pneumocystis in Iran
| Study Population | Subjects No. | Diagnostic Specimen | Diagnostic methods | Colonization or Infection with Pneumocystis | Date of Study Publication (reference) |
|---|---|---|---|---|---|
| Orphan children | 40 | Autopsy lung | H&E stain | 12.5% | 1964 (12) |
| Orphan children | 50 | Serum, Respiratory secretions | Immuoeletrophresis, Giemsa stain | NA | 1972 (13) |
| Immunocopetent rats | 158 | Autopsy lung | H&E, GMS, Giemsa stains | 0% | 2006 (14) |
| Immunosuppressed rats | 15 | Respiratory secretions | 100% | ||
| HIV infected patients | 52 | ND | ND | 0% | 2006 (19) |
| Immunosuppressed rats | 20 | BAL, LH, OS | GMS, Giemsa stains PCR |
NA | 2007 (15) |
| HIV infected patients | 12 | BAL | IF stain | 100% | 2007 (20) |
| Immunocopetent rats | 4 | BAL, LH,OS | GMS stain | NA | 2008 (16) |
| Immunosuppressed rats | 13 | PCR | |||
| Immunosuppressed rats | 22 | BAL, LH,OS | GMS, Giemsa stains | NA | 2008 (17) |
| Immunosuppressed patients (Receiving prednisolone) | 2 | BAL | IF stain | 100% | 2008 (21) |
| Immunosuppressed rats | 6 | LH | Giemsa stain | NA | 2008 (18) |
| HIV infected patients | 120 | ND | ND | 22.5% | 2010 (22) |
| HIV infected patients | 177 | ND | ND | 4.5% | 2011 (23) |
BAL: Bronchoalveolar lavage, GMS: Gomori's Methenamine Silver, H & E: Hematoxylin & Eosin, IF: Immunofluorescence, LH: lung homogenate, NA: Not applicable, ND: Not determined, OS: Oral swab, PCR: Polymerase chain reaction