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. 2013 Apr 23;8(4):e62399. doi: 10.1371/journal.pone.0062399

Table 1. The demographics and clinical outcomes of the patients.

Variables APA IHA NAG P value
APA VS NAG IHA VS NAG IHA VS APA
Age 51.2±8.5 52.6±6.5 49.2±4.3 0.227 0.219 0.098
Sex, M/F 12/18 6/9 5/7 1 1 1
Blood pressure
Systolic blood pressure (mmHg) 167.4±6.1 158.2±4.9 148.4±6.7 0.359 0.893 0.403
Diastolic blood pressure (mmHg) 107.1±5.9 105.6±5.1 97.8±54.2 0.536 0.948 0.583
Water balance
Oral water intake (mL) 2193±92 1927±110 1379±87 0.037 0.013 0.732
Urine volume (mL) 2765±114 2583±75 1728±96 0.038 0.008 0.211
Serum physiological parameters
Serum potassium (mmol/L) 2.47±0.21 2.81±0.32 4.56±0.55 0.003 0.007 0.004
Serum aldosterone (pmol/L) 872±190 785±189 287±146 0.021 0.015 0.037
Basis plasma renin activity (ng·ml−1·h−1) 0.14±0.18 0.21±0.35 1.49±0.25 0.041 0.038 0.789
Serum sodium (mmol/L) 146.8±1.7 142.9±2.7 137.3±3.2 0.578 0.427 0.874
Serum chlorine (mmol/L) 101.8±3.1 99.5±2.4 98.8±3.5 0.753 0.668 0.947
Urinary physiological parameters parameters
24 h urinary potassium (mmol/L) 115.3±29.8 93.3±33.6 64.4±22.3 0.001 0.043 0.038
24 h urinary aldosterone (ug) 37.1±5.6 32.6±7.2 15.4±4.9 0.029 0.038 0.041
24 h urinary sodium (mmol/L) 202.6±35.3 188.1±29.8 215.4±47.7 0.493 0.387 0.582
24 h urinary chlorine (mmol/L) 189.6±56.9 217.7±43.5 202.5±67.5 0.294 0.198 0.781

APA aldosterone-producing adenomas; IHA idiopathic hyperaldosteronism; NAG normal adrenal gland.