Table 1. The demographics and clinical outcomes of the patients.
Variables | APA | IHA | NAG | P value | ||
APA VS NAG | IHA VS NAG | IHA VS APA | ||||
Age | 51.2±8.5 | 52.6±6.5 | 49.2±4.3 | 0.227 | 0.219 | 0.098 |
Sex, M/F | 12/18 | 6/9 | 5/7 | 1 | 1 | 1 |
Blood pressure | ||||||
Systolic blood pressure (mmHg) | 167.4±6.1 | 158.2±4.9 | 148.4±6.7 | 0.359 | 0.893 | 0.403 |
Diastolic blood pressure (mmHg) | 107.1±5.9 | 105.6±5.1 | 97.8±54.2 | 0.536 | 0.948 | 0.583 |
Water balance | ||||||
Oral water intake (mL) | 2193±92 | 1927±110 | 1379±87 | 0.037 | 0.013 | 0.732 |
Urine volume (mL) | 2765±114 | 2583±75 | 1728±96 | 0.038 | 0.008 | 0.211 |
Serum physiological parameters | ||||||
Serum potassium (mmol/L) | 2.47±0.21 | 2.81±0.32 | 4.56±0.55 | 0.003 | 0.007 | 0.004 |
Serum aldosterone (pmol/L) | 872±190 | 785±189 | 287±146 | 0.021 | 0.015 | 0.037 |
Basis plasma renin activity (ng·ml−1·h−1) | 0.14±0.18 | 0.21±0.35 | 1.49±0.25 | 0.041 | 0.038 | 0.789 |
Serum sodium (mmol/L) | 146.8±1.7 | 142.9±2.7 | 137.3±3.2 | 0.578 | 0.427 | 0.874 |
Serum chlorine (mmol/L) | 101.8±3.1 | 99.5±2.4 | 98.8±3.5 | 0.753 | 0.668 | 0.947 |
Urinary physiological parameters parameters | ||||||
24 h urinary potassium (mmol/L) | 115.3±29.8 | 93.3±33.6 | 64.4±22.3 | 0.001 | 0.043 | 0.038 |
24 h urinary aldosterone (ug) | 37.1±5.6 | 32.6±7.2 | 15.4±4.9 | 0.029 | 0.038 | 0.041 |
24 h urinary sodium (mmol/L) | 202.6±35.3 | 188.1±29.8 | 215.4±47.7 | 0.493 | 0.387 | 0.582 |
24 h urinary chlorine (mmol/L) | 189.6±56.9 | 217.7±43.5 | 202.5±67.5 | 0.294 | 0.198 | 0.781 |
APA aldosterone-producing adenomas; IHA idiopathic hyperaldosteronism; NAG normal adrenal gland.