Table 3. The association between p-AKT and p-mTOR activities and the clinicopathological characteristics in the adrenocortical lesions of primary aldosteronism patients.
Variables | Number | p-AKT | p-mTOR | ||||||
− | + | ++ | +++ | − | + | ++ | +++ | ||
Gender | |||||||||
Male | 23 | 8 | 9 | 5 | 1 | 6 | 10 | 7 | 0 |
Female | 34 | 13 | 17 | 3 | 1 | 10 | 12 | 11 | 1 |
Age (Years) | |||||||||
<50 | 28 | 11 | 9 | 8 | 0 | 8 | 13 | 6 | 1 |
≥50 | 29 | 10 | 12 | 6 | 1 | 8 | 15 | 6 | 0 |
Blood pressure | |||||||||
Normal | 10 | 6 | 3 | 1 | 0 | 3 | 5 | 2 | 0 |
High | 47 | 15 | 19 | 12 | 1 | 13 | 18 | 16 | 0 |
Plasma aldosterone | |||||||||
Normal | 18 | 10 | 7 | 1 | 0 | 6 | 11 | 1 | 0 |
High | 39 | 11 | 12 | 16 | 0# | 10 | 11 | 16 | 2# |
Serum K | |||||||||
Normal | 17 | 9 | 7 | 1 | 0 | 5 | 7 | 5 | 0 |
Low | 40 | 12 | 21 | 6 | 1 | 11 | 15 | 14 | 0 |
PRA | |||||||||
Normal | 27 | 9 | 11 | 7 | 0 | 5 | 15 | 6 | 1 |
Low | 30 | 12 | 13 | 4 | 1 | 11 | 13 | 6 | 0 |
indicates that the expression of p-AKT and p-mTOR was correlated with the plasma aldosterone level (P = 0.008, P = 0.027).