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. 2013 Apr 23;8(4):e62399. doi: 10.1371/journal.pone.0062399

Table 3. The association between p-AKT and p-mTOR activities and the clinicopathological characteristics in the adrenocortical lesions of primary aldosteronism patients.

Variables Number p-AKT p-mTOR
+ ++ +++ + ++ +++
Gender
Male 23 8 9 5 1 6 10 7 0
Female 34 13 17 3 1 10 12 11 1
Age (Years)
<50 28 11 9 8 0 8 13 6 1
≥50 29 10 12 6 1 8 15 6 0
Blood pressure
Normal 10 6 3 1 0 3 5 2 0
High 47 15 19 12 1 13 18 16 0
Plasma aldosterone
Normal 18 10 7 1 0 6 11 1 0
High 39 11 12 16 0# 10 11 16 2#
Serum K
Normal 17 9 7 1 0 5 7 5 0
Low 40 12 21 6 1 11 15 14 0
PRA
Normal 27 9 11 7 0 5 15 6 1
Low 30 12 13 4 1 11 13 6 0
#

indicates that the expression of p-AKT and p-mTOR was correlated with the plasma aldosterone level (P = 0.008, P = 0.027).