Table 1. Clinical phenotypes of family members in the Chinese pedigree.

Family ID	Person ID	Gender	Affection status	Age (years)	Skin		Sparse hair	Hypohidrosis	Facial features	Eczema	Tooth existing (Hypodontia)	Nail dysplasia	Sweat glands dysplasia	Other Manifestations
					Hypoplastic	Thin & wrinkled
I	II3	F	C	50	–	–	+	–	–	–	NM	–	–
I	III1	M	A	25	++	++	++	+	+	+	13, 23	+	++
I	III2	M	A	23	++	++	++	++	+	+	anodontia	+	++

A: affected; C: carrier; F: female; M: male; NM: no missing; +: positive; number of ‘+’ symbols reflects the degree of these clinical features; -: negative; 13: Right maxillary canine; 23: Left maxillary canine.