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. 2013 Apr 23;8(4):e62691. doi: 10.1371/journal.pone.0062691

Table 3. Patients having dialysis or death as an outcome, n (% of patients with each diagnosis), and relative risk, RR (95% Confidence interval), in each AKI category in the Development versus Validation cohorts.

Development cohort Validation cohort
Patients with outcome n(%) No Structural-AKI Structural-AKI No Structural-AKI Structural-AKI
No Functional-AKI 9 (8.5) 8 (21.1) 10 (9.7) 6 (14.6)
Functional-AKI 8 (17.8) 20 (30.7) 6 (13.0) 19 (30.2)
Relative Risk of outcome (95% Confidence interval)
No Functional-AKI 1 (referent) 2.48 (1.94 to 2.81) 1 (referent) 1.51 (1.26 to 1.62)
Functional-AKI 2.09 (1.70 to 2.31) 3.62 (2.95 to 4.16) 1.34 (1.16 to 1.42) 3.11 (2.53 to 3.55)

Functional-AKI: Plasma creatinine >26.4 µmol/L (0.3 mg/dl) in 48 hours or 50% in 7 days.

Structural-AKI: Urinary NGAL >140 ng/ml.

Outcome: Need for dialysis or death within 30 days.