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. 2013 Apr 23;8(4):e62691. doi: 10.1371/journal.pone.0062691

Table 4. Structural-AKI thresholds for severity stages based on equivalent sensitivity (62%) to Functional-AKI.

Functional-AKI stage NGAL AP GGT Cystatin C IL-18 KIM1 α-GST π-GST
ng/ml U/L U/L mg/L pg/ml pg/ml μg/L μg/L
1. ≥26.4 µmol/L in 48h or ≥50% in 7d 140 11.2 128 0.95 118 1850 5.13 14.6
2. ≥100% in 7d 438 28.2 254 7.77 735 6530 31.1 59.3
3. ≥200% or increase to ≥353.6 µmol/L in 7d 2710 50.2 452 17.0 2330 9760 82.1 141