Table 4. Structural-AKI thresholds for severity stages based on equivalent sensitivity (62%) to Functional-AKI.
Functional-AKI stage | NGAL | AP | GGT | Cystatin C | IL-18 | KIM1 | α-GST | π-GST |
ng/ml | U/L | U/L | mg/L | pg/ml | pg/ml | μg/L | μg/L | |
1. ≥26.4 µmol/L in 48h or ≥50% in 7d | 140 | 11.2 | 128 | 0.95 | 118 | 1850 | 5.13 | 14.6 |
2. ≥100% in 7d | 438 | 28.2 | 254 | 7.77 | 735 | 6530 | 31.1 | 59.3 |
3. ≥200% or increase to ≥353.6 µmol/L in 7d | 2710 | 50.2 | 452 | 17.0 | 2330 | 9760 | 82.1 | 141 |