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. 2013 Apr 23;8(4):e62138. doi: 10.1371/journal.pone.0062138

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© 2013 Wang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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GFP (green) represents the over expressed GATA4 protein, and DAPI (blue) represents the location of the nucleus. The subcellular localization of pEGFP-GATA4 wild-type (WT) and mutant-type proteins shows that wild-type GATA4 completely localized to the nucleus, while mutated GATA4 proteins were partially distributed in the cytoplasm besides the nucleus.