Table 1. Participants demographics.
| Group 1 (1.5T GE Signa scanner) | Group 2 (3.0T Philips Achieva scanner) | |||||
| HealthyControls | MTLE+HS | Unaffected siblingsof MTLE+HS | Healthycontrols | MRI-negativeTLE patients | Unaffected siblings ofMRI-negative TLE | |
| Number | 58 | 70 | 50 | 28 | 31 | 33 |
| Age: mean (SD) | 31.5 (9.0) | 36.6 (11.4) | 36.8 (10.3) | 34.7 (8.8) | 37.2 (9.6) | 37.1 (9.8) |
| Gender: number (%) | ||||||
| Male | 27 (46.6%) | 30 (42.9%) | 20 (40%) | 12 (42.9%) | 12 (38.7%) | 12 (36.4%) |
| Female | 31 (53.4%) | 40 (57.1%) | 30 (60%) | 16 (57.1%) | 19 (61.3%) | 21 (63.6%) |
| Side of seizure activity | ||||||
| Left | – | 35 | 27* | – | 12 | 12* |
| Right | – | 35 | 23* | – | 12 | 12* |
| Bilateral | – | 0 | 0 | – | 3 | 2* |
| Undetermined | – | 0 | 0 | – | 5 | 7* |
| Age at onset: mean (SD) | – | 14.2 (11.3) | – | – | 17.8 (10.9) | – |
| Epilepsy duration: mean (SD) | – | 22.4 (14.4) | – | – | 19.2 (12.3) | – |
| IPIs: number (%) | ||||||
| Febrile Seizures | 0 | 33 (47.1%) | 0 | 0 | 6 (19.4%) | 0 |
| Intracranial Infection(s) | 0 | 4 (5.7%) | 0 | 0 | 1 (3.2%) | 0 |
| Status epilepticus | 0 | 9 (12.8%) | 0 | 0 | 2 (6.4%) | 0 |
| Underwent Surgery: number (%) | – | 32 (45.7%) | – | – | 1 (3.2%) | – |
SD: standard deviation; IPIs: initial precipitating insults;
*
indicates the number of unaffected siblings based on the side of seizure activity in patients.