Table 1. In vitro development of the chimeric embryos produced by injection or aggregation method.
Donor cells | Method | Stage of host embryos | No. of embryos cultured | Blastocysts (%) | Chimeric blastocysts (%) |
ICM | Injection | Mourla | 29 | 27 (93.1) | 24 (82.8) |
ICM | Aggregation | Morula** | 24 | 23 (95.8) | 20 (83.3) |
ICM | 4–8 cell** | 26 | 23 (88.5) | 17 (65.4) | |
Morula* | Morula* | 34 | 31 (91.2) | 24 (70.6) | |
Morula* | 4–8 cell* | 26 | 23 (88.5) | 17 (65.4) | |
4–8 cell* | 4–8 cell* | 46 | 37 (80.4) | 27 (58.7) |
Blastomeres isolated from single embryos.
Blastomeres isolated from two embryos.