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. 2013 Apr 23;8(4):e61904. doi: 10.1371/journal.pone.0061904

Table 5. Induction of proapoptotic molecules in lungs from pigs infected with Zaire ebolavirus.

Gene Description Fold change
DPI 3 DPI 5 DPI 7
CASP1 Caspase 1 2 13 12
CASP3 Caspase 3 1 3 3
CASP1/4 Caspase 1/3 2 6 5
CASP8 Caspase 8 1 3 2
CASP15 Caspase 15 1 3 5
CARD6 Caspase recruitment domain family 2 4 4
AATYK Apoptosis-associated tyrosine kinase 2 1 4 4
FADD Fas (TNFRSF6)-associated via death domain 2 3 3
FAS TNF receptor superfamily, member 6 2 5 5
TRAF3 TNF receptor-associated factor 3 2 6 7
TNIP3 TNFAIP3 interacting protein 3 isoform 3 3 10 14
AIF1 Allograft inflammatory factor 1 1 3 3

Data was obtained by microarray analysis of RNA from lungs of pigs infected with Zaire ebolavirus in experiment 1. Numbers represent fold change in transcription relative to tissues from uninfected controls. DPI, days post infection. N = 2 pigs for controls, DPI 3, 5 and 7.