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. 2013 Apr 23;8(4):e61656. doi: 10.1371/journal.pone.0061656

Figure 8. Effect of glutamate without or with local HPC on retinal histology.

Figure 8

Representative photomicrographs showing histological appearance of retinas obtained 7 days after injection of vehicle (A, D) or glutamate without (B, E) or with local HPC applied 24 h before glutamate injection (C, F). Glutamate induced alteration in the retinal structure (upper panel) and GCL Brn3a(+) cell number (lower panel), whereas local HPC prevented histological alterations from glutamate damage. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; ONL, outer nuclear layer, OS, outer segment of photoreceptors.