Table 1. Distribution of top ten functional categories among core paralogous proteins in 17 Nocardiopsis genomes.

Genome	Functional categories
	Transcriptional regulator					ABC transporter	shortchain dehydrogenase	MajorFacilitatorsuperfamily	serine/threonineproteinkinase	hydrolase	methyltransferase	signaltransductionhistidinekinase	NRPSs/PKSs	cytochromeP450
	TetR	XRE	LuxR	MerR	other familiesa
N. alba	43	12	16	14	72	101	28	33	29	23	24	18	15	9
N. alkaliphila	27	14	14	5	61	98	25	21	21	19	18	11	10	11
N. baichengensis	46	23	17	9	85	107	30	24	16	25	22	18	16	9
N. chromatogenes	50	23	17	12	92	125	31	33	19	30	21	18	24	10
N. dassonvillei	60	19	18	14	77	123	48	27	26	26	23	18	14	12
N. ganjiahuensis	62	18	20	17	96	161	45	36	34	28	27	22	10	17
N. gilva	45	17	12	13	70	94	21	26	13	17	19	13	11	10
N. halophila	49	19	17	12	90	106	32	28	21	26	20	17	11	10
N. halotolerans	49	15	18	12	80	112	40	30	27	25	27	18	14	13
N. kunsanensis	27	13	14	5	51	90	25	18	19	18	18	15	10	10
N. lucentensis	47	21	15	8	76	101	34	23	29	19	21	13	17	7
N. potens	67	20	21	16	83	108	33	36	29	31	27	24	18	9
N. prasina	44	16	12	14	87	129	43	28	21	21	21	14	11	12
N. salina	32	11	9	3	64	107	31	16	23	21	20	10	9	10
N. synnemataformans	60	27	23	20	86	132	45	30	29	23	22	18	17	13
N. valliformis	52	25	18	13	83	145	35	34	46	24	22	12	22	16
N. xinjiangensis	31	14	14	7	57	105	25	17	18	21	20	16	15	7

^*The other families include ArsR, LacI, MarR, AraC, SARP, IclR, PadR, PucR, CopY, winged helix family, Crp/Fnr, and RpiR transcription factor.