Table 1. Clinicopathologic characteristics of patients with GC.

Parameter	Total	Percentage	95%CI of mean log2 fold		P
	samples		change±SEM
Age(years)
≥60	112	47.3%	−0.307	(−0.969–0.355)	0.847
<60		52.7%	−0.216	(−0.877–0.444)
Gender
Male	112	84.8%	−0.413	(−0.918–0.091)	0.118
Female		15.2%	0.601	(−0.561–1.762)
Location
Proximal	113	30.9%	−0.124	(−0.956–0.708)	0.765
Body		41.6%	−0.45	(−1.125–0.225)
Distal		27.4%	−0.085	(−1.097–0.927)
Lauren's classification
Intestinal	72	18.1%	0.765	(−0.999–2.528)	0.397
Diffuse		68.1%	−0.213	(−0.912–0.485)
Mixed		13.9%	−0.508	(−2.283–1.268)
Grade
Well and Moderate	62	21.0%	0.434	(−1.324–2.192)	0.366
differentiated
Poorly differentiated		79.0%	−0.297	(−1.010–0.416)
Tumor size
T1–T2	111	17.1%	0.282	(−0.701–1.264)	0.286
T3		21.6%	0.174	(−0.985–1.334)
T4		61.3%	−0.539	(−1.136–0.058)
Lymphatic invasion
N0–N1	111	67.6%	−0.143	(2.436–0.281)	0.533
N2–N3		32.4%	−0.457	(−1.323–0.410)
Nodal involvement
Negative	110	90.9%	−0.314	(−0.806–0.178)	0.306
Positive		9.1%	−0.008	(−1.526–1.510)
Stage
I–II	110	35.5%	0.387	(−0.420–1.195)	0.047*
III–IV		64.5%	−0.591	(−1.165–0.018)
Perineural Invasion
Negative	81	56.8%	−0.174	(−0.838–0.490)	0.634
Positive		43.2%	−0.424	(−1.265–0.417)
Ki67
1+2	27	25.9%	0.925	(−2.863–4.713)	0.163
3+4		74.1%	−0.724	(−1.789–0.341)
Her2 amplification
Negative	41	48.8%	−0.227	(−1.309–0.855)	0.348
Positive		51.2%	0.039	(−1.044–1.121)
Top2a
0+1	42	42.9%	−0.0988	(−1.120–0.923)	0.957
2+3		57.1%	0.134	(−1.014–1.283)
CA199
<37	29	75.9%	0.092	(−0.859–1.042)	0.258
>37		24.1%	−1.115	(−4.032–1.802)
CA724
<6.1	28	67.9%	−0.424	(−1.226–0.378)	0.538
>6.1		32.1%	0.135	(−2.724–2.994)