Fig. 2.

Recombinant IGFBP-5 increased the proliferation of the VSMCs from WKY. Cells were treated with IGFBP-5 (50, 100, and 200 ng/ml) for 24 hrs. Cell proliferation was determined by counting cells (A) and performing an MTT assay (B). Results are represented as the mean±S.E.M. (n=4). ^*p value<0.05 compared with VSMCs of WKY. ^**p value<0.001 compared with VSMCs of WKY.