Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Tumor mutational profiles pre-treatment and upon disease progression
| Gene | Mutations | |
|---|---|---|
| Pre-study† | Progressive disease† | |
| BRAF | V600E | V600E |
| CCND3 | amplification | amplification |
| ARID1A | S90fs*11 | S90fs*11 |
| RB1 | S807* | S807* |
| KRAS | - | G12D |
| TP53 | - | R175H |
| CDKN2A | - | R24fs*20 |
Both tumor biopsies were profiled using the FoundationOne™ next-generation sequencing assay.
