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. Author manuscript; available in PMC: 2014 Apr 19.
Published in final edited form as: J Org Chem. 2013 Mar 29;78(8):3737–3754. doi: 10.1021/jo4002432

Table 1.

Optimization of the Cyclocarbonylation Reaction Conditionsgraphic file with name nihms-462511-t0002.jpg

Entry [Rh(CO)2CI]2 (mol %) Time (h) T(°C) Product and yield (%) Solvent
1 10 3 90 35c (95); 36c (0) PhMe
2 5 9 90 35c (75); 36c (9) PhMe
3 10 7 120 35c (61); 36c (35) PhMe
4 5 7 120 35c (42); 36c (48) PhMe
5 1 24 120 35c (29); 36c (26) PhMe
6a 10 24 40 35cb (72); 36c (0) DCE
a

PPh3 (30 mol %), AgBF4 (22 mol %);

b

Yield based on recovered starting material (conversion : 54%)