Table 2.
Baseline Comorbidity, Depression, and Function Characteristics by Self-Reported Premenstrual Exacerbation
| |
|
|
PME |
Analyses |
||||
|---|---|---|---|---|---|---|---|---|
|
Measure |
All (N=821) |
Yes (N=545) |
No (N=276) |
Test statistic |
p value |
|||
| Comorbidity characteristics | ||||||||
| n | % | n | % | n | % | |||
| PDSQ Agoraphobia | 105 | 12.9 | 75 | 13.8 | 30 | 11.1 | chi-squared (1)=1.19 | 0.275 |
| PDSQ Alcohol abuse | 78 | 9.6 | 56 | 10.3 | 22 | 8.1 | chi-squared (1)=0.99 | 0.320 |
| PDSQ Bulimia | 151 | 18.5 | 102 | 18.8 | 49 | 18.1 | chi-squared (1)=0.05 | 0.817 |
| PDSQ Drug abuse | 60 | 7.4 | 42 | 7.7 | 18 | 6.6 | chi-squared (1)=0.32 | 0.569 |
| PDSQ Generalized anxiety | 240 | 29.5 | 167 | 30.8 | 73 | 26.9 | chi-squared (1)=1.27 | 0.260 |
| PDSQ Hypochondriasis | 45 | 5.5 | 33 | 6.1 | 12 | 4.4 | chi-squared (1)=0.94 | 0.332 |
| PDSQ Obsessive-compulsive | 121 | 14.9 | 89 | 16.4 | 32 | 11.8 | chi-squared (1)=3.00 | 0.083 |
| PDSQ Panic | 111 | 13.6 | 72 | 13.2 | 39 | 14.4 | chi-squared (1)=0.21 | 0.650 |
| PDSQ Posttraumatic stress | 181 | 22.2 | 125 | 23.0 | 56 | 20.7 | chi-squared (1)=0.56 | 0.454 |
| PDSQ Social phobia | 304 | 37.3 | 205 | 37.7 | 99 | 36.5 | chi-squared (1)=0.10 | 0.749 |
| PDSQ Somatoform | 19 | 2.3 | 15 | 2.8 | 4 | 1.5 | chi-squared (1)=1.30 | 0.255 |
| No. psychiatric disorders | chi-squared (4)=3.79 | 0.436 | ||||||
| 0 | 250 | 30.8 | 155 | 28.7 | 95 | 35.2 | ||
| 1 | 196 | 24.2 | 136 | 25.1 | 60 | 22.2 | ||
| 2 | 155 | 19.1 | 105 | 19.4 | 50 | 18.5 | ||
| 3 | 90 | 11.1 | 63 | 11.6 | 27 | 10.0 | ||
| 4+ | 120 | 14.8 | 82 | 15.2 | 38 | 14.1 | ||
| No. moderate to severe GMCs | chi-squared (4)=10.6 | 0.032 | ||||||
| 0 | 474 | 57.7 | 308 | 56.5 | 166 | 60.1 | ||
| 1 | 182 | 22.2 | 114 | 20.9 | 68 | 24.6 | ||
| 2 | 103 | 12.5 | 77 | 14.1 | 26 | 9.4 | ||
| 3 | 36 | 4.4 | 23 | 4.2 | 13 | 4.7 | ||
| 4+ | 26 | 3.2 | 23 | 4.2 | 3 | 1.1 | ||
| Mean | SD | Mean | SD | Mean | SD | |||
|---|---|---|---|---|---|---|---|---|
| CIRS No. problems | 2.58 | 2.02 | 2.75 | 2.07 | 2.22 | 1.88 | H(1)=13.0 | <0.001 |
| CIRS Ratings sum | 3.40 | 2.99 | 3.66 | 3.16 | 2.88 | 2.56 | H(1)=11.0 | 0.001 |
| CIRS Severity index | 1.11 | 0.59 | 1.13 | 0.57 | 1.07 | 0.62 | H(1)=1.75 | 0.185 |
| Depression and function characteristics | ||||||||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |||
| Anxious features | 420 | 51.2 | 295 | 54.1 | 125 | 45.3 | chi-squared (1)=5.73 | 0.017 |
| Atypical features | 179 | 21.8 | 122 | 22.4 | 57 | 20.7 | chi-squared (1)=0.29 | 0.587 |
| Melancholic features | 184 | 22.4 | 123 | 22.6 | 61 | 22.1 | chi-squared (1)=0.02 | 0.879 |
| Mean | SD | Mean | SD | Mean | SD | |||
|---|---|---|---|---|---|---|---|---|
| HRSD17 | 21.8 | 5.24 | 21.8 | 5.21 | 21.8 | 5.32 | t(819)≤0.01 | 0.997 |
| IDS-C30 | 39.2 | 9.59 | 39.3 | 9.54 | 39.0 | 9.70 | t(814)=0.51 | 0.612 |
| QIDS-C16 | 17.2 | 3.20 | 17.0 | 3.23 | 17.5 | 3.11 | t(815)=1.91 | 0.056 |
| QIDS-SR16 | 16.7 | 3.96 | 16.5 | 4.04 | 17.3 | 3.74 | t(816)=2.69 | 0.007 |
| Q-LES-Q | 38.8 | 14.0 | 39.4 | 14.0 | 37.7 | 14.1 | t(774)=1.53 | 0.126 |
| SF-12 Mental | 24.1 | 7.88 | 24.4 | 7.73 | 23.4 | 8.14 | t(774)=1.73 | 0.084 |
| SF-12 Physical | 51.6 | 10.9 | 50.9 | 10.9 | 52.8 | 10.8 | H(1)=6.02 | 0.014 |
| WSAS | 25.3 | 8.6 | 25.0 | 8.56 | 26.0 | 8.65 | t(774)=1.66 | 0.098 |
CIRS, Cumulative illness rating scale; GMC, general medical comorbidity; HRSD17, 17-item Hamilton rating scale for depression; IDS-C30, 30-item Inventory of depressive symptomatology: Clinician-rated; PDSQ, Psychiatric diagnostic screening questionnaire; PME, premenstrual exacerbation (reported); QIDS-C16, 16-item Quick inventory of depressive symptomatology: Clinician-rated, QIDS-SR16, 16-item Quick inventory of depressive symptomatology: Self-rated; Q-LES-Q, Quality of life enjoyment and satisfaction questionnaire; SF-12, Short-form health survey; WSAS Work and social adjustment scale.