Table 1.

Lobe-Wise Connection Strength Changes Between Awake Resting and Sedation

		Awake		Sedation
Lobe–lobe interactions		Mean	SD	Mean	SD	t	p-Value
Frontal–	Frontal	0.2865	0.1499	0.2644	0.1417	−1.5882	0.1130
	Parietal	0.2532	0.1276	0.2308	0.1072	−1.5107	0.1321
	Occipital	0.1466	0.0320	0.1157	0.0215	−3.3109	0.0020
	Temporal	0.2155	0.1157	0.2044	0.1025	−0.8595	0.3908
	Subcortical	0.1999	0.0922	0.1707	0.0662	−2.2568	0.0254
Parietal–	Parietal	0.3455	0.1729	0.3326	0.1712	−0.3703	0.7120
	Occipital	0.1808	0.0368	0.1924	0.0720	0.8950	0.3738
	Temporal	0.1818	0.0727	0.1776	0.0815	−0.2332	0.8163
	Subcortical	0.1399	0.0393	0.1349	0.0320	−0.2948	0.7717
Occipital–	Occipital	0.3867	0.1593	0.4153	0.2115	0.9929	0.3222
	Temporal	0.1880	0.0756	0.1697	0.0624	−1.1587	0.2501
	Subcortical	0.1305	0.0180	N.A.	N.A.	N.A.	N.A.
Temporal–	Temporal	0.2713	0.1373	0.2736	0.1326	0.1136	0.9097
	Subcortical	0.1734	0.0587	0.1420	0.0297	−3.0746	0.0028
Subcortical–	Subcortical	0.3835	0.1213	0.3178	0.1444	−1.8415	0.0710

Differences evaluated with two-group t-test on significant positive connections in the group mean connectivity matrices. Bold values: significant at p<0.05. Underscored bold values: significant at false discovery rate–corrected p<0.05. There were no significant occipital–subcortical connections during sedation. N.A., not applicable; SD, standard deviation.