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Single voxel magnetic resonance spectroscopy. (A) With short echo time (35 ms) of the right frontal white matter from Patient 2 at 24 months of age demonstrating a relatively high myoinositol (mI) peak and a relatively low N-acetyl aspartate peak (NAA, circled) in relation to the creatine (Cr) and choline (Cho) peaks signifying immaturity. Magnetic resonance spectroscopy obtained with similar acquisition parameters of a normal 24-month-old child is shown (B) for comparison.
