Table 3.
Timepoint | Subjects, No. | Seroprotectiona (%) | Geometric Mean Titer |
---|---|---|---|
(95% CI) | (95% CI) | ||
Birth | 106 | 65 (55–74) | 55 (43–70) |
3 mo | 97 | 26 (17–36)b | 14 (12–17)c |
6 mo | 59 | 12 (5–23)b | 13 (11–17)c |
Abbreviation: CI, confidence interval.
Infant antibody levels at birth, 3 months, and 6 months were analyzed for those infants with available data whose mothers received both doses of vaccine and delivered subsequent to the 10-day postvaccine dose 2 timepoint.
a Seroprotection defined as hemagglutination inhibition titer ≥40.
b P < .0001 (McNemar test) for the comparison to seroprotection at birth.
c P < .0001 (sign test) for the comparison to geometric mean titer at birth.