Figure 3. Enhanced autophagy alleviated chronic ethanol-induced liver steatosis and liver injury.
Mice were treated with control diet, 29% (A–E) or 36% (B–E) ethanol diet and then given rapamycin every other day for three times in the week before sacrifice, or CBZ (12.5 mg/kg) once on the day before sacrifice. Cryosections of the livers were stained with Bodipy 493/503 (A). The numbers of LDs were quantified (B). Hepatic TG (C), blood TG (D) and ALT (E) levels were determined. *: p<0.01 (n=3–13).