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. 2013 Apr 19;7:351–360. doi: 10.2147/DDDT.S32252

Figure 1.

Figure 1

The guanylyl cyclase C agonists.

Notes: Known primary amino acid structures of the agonists of guanylyl cyclase C. Residues shown in green on the structures on the right indicate amino acid substitutions in synthetic ligands compared with respective biological homologs. The amino acid sequence for ST reflects that of the heat-stable enterotoxin isoform STh produced by Escherichia coli.