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Alignment of amino acid residues of HIV-1 subtype C (residues 151–288). The test consensus was generated from 37 viruses. The global subtype B and C consensus sequences were obtained also from HIV sequence database. The conserved residue E, which is an integral part of the DDE motif is noted (+). All positions that agree with the global subtype B consensus sequence are denoted by a dot (.); while ambiguous amino acids are denoted by an X.
