Table 1.
Overview on the analyzed tissue collectives.
| Prostate biopsies with normal, tumor free tissue (30% to 50% epithelia) from | |||
|---|---|---|---|
| Groups | Healthy men (tumor negative) | Healthy men (with initial suspicion for prostate cancer (PCa), but found to be tumor negative) | PCa patients (with proven malignant prostate tumor) |
| Number of individuals | n = 17 | n = 14 | n = 31 |
| Years of age (10%- & 90%-quantiles) | 51 to 64 | 54 to 75 | 54 to 66 |
| Diagnostics | negative palpation, negative diagnostic biopsy series | negative or unclear palpation, multiple negative diagnostic biopsy series | unclear or positive palpation, ≥one tumor positive diagnostic biopsy |
| low prostate specific antigen (PSA) level (mean 0.78 ng/mL [±0.26 SD]) | elevated PSA level (mean 6.44 ng/mL [±4.82 SD]) | elevated PSA level (mean 7.97 ng/mL [±5.21 SD]) | |
| Designations | Tumor-negative/normal PSA group (TN-nPSA group) | Tumor-negative/high PSA group (TN-hPSA group) | Tumor-positive group (TP group) |
| Note | groups representing men with elevated PSA levels submitted to diagnostic biopsy-taking in clinical routine | ||