Table 3.
PLA2 family (adapted from [91]).
| Type | Group | Subgroup | Origin or commun source |
|---|---|---|---|
| sPLA2 | I | A | Cobras and kraits |
| I | B | Human/porcine pancreas | |
| II | A | Rattlesnake/human synovial | |
| II | B | Gaboon viper | |
| II | C | Rat/murine testis | |
| II | D | Human/murine pancreas/spleen | |
| II | E | Human/murine brain/heart/uterus | |
| II | F | Human/murine testis/embryo | |
| III | Lizard/bee | ||
| V | Human/murine heart/lung/macrophage | ||
| IX | Snail venom | ||
| X | Human spleen/thymus/leucocyte | ||
| XI | A | Green rice shoots (PLA2-I) | |
| XI | B | Green rice shoots (PLA2-II) | |
| XII | A | Human/murine | |
| XII | B | Human/murine | |
| XIII | Parvovirus | ||
| XIV | Symbiotic fungus/bacteria | ||
| cPLA2 | IV | A(α) | Human macrophage-like U937 cells/Platelets/Raw 264.7/rat kidney, ubiquitous |
| IV | B(β) | Human pancreas/liver/heart/brain/ubiquitous | |
| IV | C(γ) | Human heart/skeletal muscle | |
| IV | D(δ) | Murine placenta | |
| IV | E(ɛ) | Murine heart/skeletal muscle/testis/thyroid | |
| IV | F(η) | Murine thyroid/stomach | |
| iPLA2 | VI | A(β) | Human/murine |
| VI | B(γ) | Human/murine | |
| VI | C(δ) | Human/murine | |
| VI | D(ɛ) | Human | |
| VI | E(ζ) | Human | |
| VI | F(η) | Human | |
| PAF-AH | VII | A(lipoprotein-associated-PLA2) | Human, murine, porcine, bovine |
| VII | B(PAF-AH II) | Human, bovine | |
| VIII | A(α1) | Human | |
| VIII | B(α2) | Human | |
| Lysosomal PLA2 | XV | Human, murine, bovine | |
| Adipose PLA | XVI | Human,mouse |