Table 7.

PLC family (according to [319,343,356,357,359,368]).

Type	Group	Origin
Non-specific PLC		Mammalian
PI-specific	PLC-β PLCB1, PLCB2, PLCB3, PLCB4	Mammalian
PI-specific	PLC-γ PLCG1, PLCG2	Mammalian
PI-specific	PLC-δ PLCD1, PLCD3, PLCD4	Mammalian
PI-specific	PLC-ɛ PLCE1	Mammalian
PI-specific	PLC-η PLCH1, PLCH2	Mammalian
PI-specific	PLC-ζ PLCZ1	Mammalian
Phospholipase C-like	PLCL1, PLCL2	Mammalian
Zinc-dependent prokaryotic PLC		Bacterial
PI-DAG-lyase		Trypanosome
SMase	Neutral SMase1	Mammalian
	Neutral SMase2 (SMPD3)	Mammalian
	Neutral SMase3	Mammalian
	Lysosmal acid SMase	Mammalian
	Secreted zinc-dependent acid SMase	Mammalian
	Alkaline SMase	Mammalian