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. 2013 Mar 1;14(3):4841–4853. doi: 10.3390/ijms14034841

Figure 2.

Figure 2

Amino acid sequence of S. sq VEGFR, and its strong homology with human VEGFR. (a) Isolation of cDNA related to VEGFR gene from ascidian, H. roretzi; (b) Schematic diagram of VEGFR of H. roretzi in comparison to human Flt-1 (VEGFR1). A high degree of conservation of critical tyrosine-containing residues in S. sq VEGFR and human VEGFR; (c) Sequence homology of S. sq VEGFR with human VEGFR1 in the KD2 region (157 amino acid-long sequence; ATVD—RLAE in S. sq VEGFR). [*]: identical amino acids with the VEGFR-related sequence in the middle; (d) Sequence homology among ascidian VEGFRs (S. sq VEGFR, B. schlosseri VEGFR, and C. intestinalis VEGFR) in the KD2 region. [*]: identical amino acids with the VEGFR-related sequence in the middle.