Figure 5. Effects of genetic deletion of endothelial nitric oxide synthase (eNOS) on lymphatic vessel contractile function.
Lymphatic contractile function was directly compared between wild-type (WT; filled points) and eNOS−/− vessels (open points). End diastolic diameter (EDD; A), tone (B), contraction amplitude (AMP; C), ejection fraction (EF; D), contraction frequency (FREQ; E) and fractional pump flow (FPF; F) were compared between the two genotypes. All data are means (± SEM). When error bars appear missing, they are actually contained within the data points. Data in each graph were fit to a curve as appropriate, except for tone and FPF, which were necessarily splined. *Filled versus open data points differ significantly (P < 0.05).