Table 1.
Blood gas analysis of NBCn1 wild-type and NBCn1 knock-out mice taken at the end of the experiment
| Genotype | pH |
 (mmHg) |
 (mmHg) |
 (%) |
HCO3− (mmol l−1) | ABE (mmol l−1) | SBE (mmol l−1) | SBC SBC (mmol l−1) |
|---|---|---|---|---|---|---|---|---|
| NBCnl (+/+; n=6) | 7.43 ± 0.02 | 41.50 ± 2.47 | 98.17 ± 9.79 | 97.00 ± 0.63 | 27.00 ± 0.97 | 3.00 ± 0.86 | 2.83 ± 0.87 | 26.83 ± 0.79 |
| NBCnl (–/–; n=8) | 7.43 ± 0.02 | 40.50 ± 1.99 | 103.50 ± 8.25 | 97.63 ± 0.42 | 26.25 ± 1.08 | 2.38 ± 1.03 | 2.50 ± 1.07 | 27.88 ± 1.59 |
Both the wild-type group and the knock-out group of mice were infused with same carotid solution for the correction of systemic acidosis caused by anaesthesia (see Methods). There was no significant difference between the two groups during the experiment. SO2, Oxygen saturation; ABE, Actual base excess; SBE, Standard base excess and SBC, Standard bicarbonate content.